The genetic editing landscape has witnessed a transformation with the revelation of Fanzor, an innovative CRISPR-like system identified within eukaryotic organisms. Discovery of Fanzor introduces a new dimension to gene editing research, presenting an alternative to the widely recognized CRISPR/Cas systems. In this review, we explore the critical facets and ramifications of the Fanzor system, shedding light on its potential applications and advantages for precise gene manipulation in complex organisms.